James L Kennedy Selected Research

Mental Disorders (Mental Disorder)

1/2021	Melatonin's neuroprotective role in mitochondria and its potential as a biomarker in aging, cognition and psychiatric disorders.
1/2019	Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa.
1/2018	GWAS-based machine learning approach to predict duloxetine response in major depressive disorder.
1/2018	Genetic testing as a supporting tool in prescribing psychiatric medication: Design and protocol of the IMPACT study.
1/2017	Investigating Cortical Inhibition in First-Degree Relatives and Probands in Schizophrenia.
4/2015	Investigation of the genetic interaction between BDNF and DRD3 genes in suicidical behaviour in psychiatric disorders.
1/2015	Investigation of TSPO variants in schizophrenia and antipsychotic treatment outcomes.
1/2013	Study of the catechol-o-methyltransferase (COMT) gene with high aggression in children.
1/2012	DISC1 and Striatal Volume: A Potential Risk Phenotype For mental Illness.
4/2008	Reward sensitivity and the D2 dopamine receptor gene: A case-control study of binge eating disorder.

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James L Kennedy Research Topics

Disease

138	Schizophrenia (Dementia Praecox) 04/2024 - 10/2002
44	Weight Gain 01/2023 - 10/2002
31	Tardive Dyskinesia 04/2024 - 07/2002
30	Bipolar Disorder (Manic Depressive Psychosis) 12/2023 - 09/2002
30	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 07/2022 - 01/2002
23	Psychotic Disorders (Schizoaffective Disorder) 11/2022 - 06/2003
20	Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive) 01/2023 - 08/2004
17	Mood Disorders (Mood Disorder) 01/2023 - 09/2002
15	Obesity 01/2020 - 04/2004
12	Mental Disorders (Mental Disorder) 01/2021 - 04/2004
9	Major Depressive Disorder (Major Depressive Disorders) 12/2023 - 05/2013
7	Movement Disorders (Movement Disorder) 01/2021 - 05/2009
7	Dyskinesias (Dyskinesia) 10/2020 - 11/2005
6	Birth Weight (Birth Weights) 01/2021 - 03/2015
6	Hyperphagia (Overeating) 01/2020 - 04/2008
6	Alcoholism (Alcohol Abuse) 01/2020 - 03/2010
6	Body Weight (Weight, Body) 08/2014 - 04/2004
5	Gambling (Pathological Gambling) 01/2023 - 12/2007
5	Alzheimer Disease (Alzheimer's Disease) 01/2021 - 12/2009
4	Anxiety Disorders (Anxiety Disorder) 01/2024 - 12/2019
4	Genetic Risk Score 12/2023 - 01/2021
4	Inflammation (Inflammations) 11/2022 - 05/2014
4	Agranulocytosis (Granulocytopenia) 12/2021 - 04/2011
4	Treatment-Resistant Schizophrenia 12/2021 - 04/2011
4	Mitochondrial Diseases (Mitochondrial Disease) 01/2021 - 05/2014
4	Binge-Eating Disorder (Binge Eating Disorder) 05/2016 - 10/2007
4	Borderline Personality Disorder (Personality Disorders, Borderline) 02/2009 - 08/2006
4	Genetic Predisposition to Disease (Genetic Predisposition) 07/2007 - 01/2002
3	Mania (Manias) 12/2023 - 08/2007
3	Drug-Related Side Effects and Adverse Reactions 12/2021 - 03/2002
3	Neuroinflammatory Diseases 01/2021 - 03/2015
3	Pain (Aches) 01/2021 - 01/2007
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021 - 10/2010
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2020 - 04/2012
3	Weight Loss (Weight Reduction) 03/2015 - 05/2010
3	Bulimia Nervosa 08/2014 - 01/2008
3	Food Addiction 01/2014 - 12/2011
2	Sleep Initiation and Maintenance Disorders (Insomnia) 12/2023 - 01/2022

Drug/Important Bio-Agent (IBA)

86	Antipsychotic Agents (Antipsychotics)IBA 01/2023 - 07/2002
33	Clozapine (Clozaril)FDA LinkGeneric 12/2021 - 10/2002
31	Dopamine (Intropin)FDA LinkGeneric 01/2021 - 03/2002
29	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2022 - 09/2002
15	Proteins (Proteins, Gene)FDA Link 01/2022 - 07/2004
15	Olanzapine (Zyprexa)FDA Link 10/2019 - 07/2009
14	Antidepressive Agents (Antidepressants)IBA 12/2023 - 08/2007
12	Messenger RNA (mRNA)IBA 01/2020 - 07/2004
11	EnzymesIBA 01/2022 - 11/2005
11	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 01/2002
10	Biomarkers (Surrogate Marker)IBA 11/2023 - 01/2011
10	Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA 12/2011 - 12/2003
9	Serotonin (5 Hydroxytryptamine)IBA 02/2014 - 05/2004
8	Genetic Markers (Genetic Marker)IBA 04/2024 - 01/2002
8	Dopamine Receptors (Dopamine Receptor)IBA 01/2018 - 03/2004
8	Glutamic Acid (Glutamate)FDA Link 02/2017 - 08/2004
7	Dopamine D2 Receptors (Dopamine D2 Receptor)IBA 01/2021 - 01/2003
6	Neurotransmitter Agents (Neurotransmitter)IBA 01/2017 - 04/2004
6	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 03/2011 - 05/2003
5	gamma-Aminobutyric Acid (GABA)IBA 01/2014 - 01/2005
5	Serotonin ReceptorsIBA 03/2013 - 04/2004
5	5-HT2A Serotonin Receptor (5 HT2A Receptor)IBA 02/2009 - 08/2004
4	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 03/2013
4	Opioid Analgesics (Opioids)IBA 07/2022 - 06/2009
4	Glutamate Receptors (Glutamate Receptor)IBA 01/2022 - 05/2009
4	Risperidone (Risperdal Consta)FDA LinkGeneric 12/2021 - 04/2010
4	Methylphenidate (Ritalin)FDA LinkGeneric 05/2016 - 10/2007
4	Monoamine Oxidase (MAO)IBA 01/2016 - 01/2007
4	Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA 01/2016 - 10/2002
4	Haloperidol (Haldol)FDA LinkGeneric 03/2013 - 04/2010
4	Oxytocin (Pitocin)FDA LinkGeneric 03/2012 - 07/2010
4	Adrenergic Agents (Adrenergic Drugs)IBA 08/2011 - 04/2002
4	Nicotine FDA Link 07/2011 - 08/2004
4	Dopamine D3 ReceptorsIBA 06/2011 - 03/2002
4	3' Untranslated Regions (3' UTR)IBA 09/2006 - 05/2005
3	Complement C4 (Complement Component 4)IBA 02/2024 - 01/2019
3	Amphetamine (Amfetamine)FDA LinkGeneric 01/2023 - 08/2010
3	Myelin-Oligodendrocyte GlycoproteinIBA 01/2023 - 08/2004
3	Mitochondrial DNA (mtDNA)IBA 07/2022 - 01/2018
3	MelatoninIBA 09/2021 - 11/2006
3	Cholinergic Agents (Cholinergics)IBA 01/2021 - 01/2004
3	Cytochrome P-450 CYP1A2 (CYP1A2)IBA 01/2021 - 10/2002
3	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 10/2020 - 01/2006
3	LipidsIBA 01/2019 - 09/2006
3	Dopamine D4 Receptors (Dopamine D4 Receptor)IBA 01/2018 - 02/2004
3	Dopamine D1 Receptors (Dopamine D1 Receptor)IBA 01/2017 - 12/2002
3	Nerve Growth Factors (Neurotrophins)IBA 01/2015 - 05/2008
3	Aminobutyrates (Aminobutyric Acid)IBA 03/2014 - 12/2009
3	CalciumIBA 01/2014 - 01/2006
3	Amino Acid Transport System X-AG (Glutamate Transporter)IBA 10/2012 - 07/2006
3	5-HT2C Serotonin ReceptorIBA 11/2010 - 11/2005
3	AntioxidantsIBA 12/2009 - 11/2005
3	Glutathione Peroxidase GPX1IBA 12/2009 - 09/2004
3	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 11/2007 - 08/2004
3	Hormones (Hormone)IBA 10/2007 - 04/2004
3	Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA 10/2007 - 10/2002
3	Protein Isoforms (Isoforms)IBA 12/2005 - 04/2005
3	Atomoxetine Hydrochloride (Strattera)FDA LinkGeneric 05/2004 - 04/2002
2	Tuberculin (PPD)IBA 12/2023 - 11/2022

Therapy/Procedure

9	Therapeutics 09/2021 - 03/2002
5	Drug Therapy (Chemotherapy) 01/2018 - 03/2002
3	Precision Medicine 01/2021 - 09/2006